12.1. Toxicity

Information on toxicity using data from tests performed on aquatic and/or terrestrial organisms shall be provided when available. This shall include relevant available data on aquatic toxicity, both acute and chronic for fish, crustaceans, algae and other aquatic plants. In addition, toxicity data on soil micro- and macroorganisms and other environmentally relevant organisms, such as birds, bees and plants, shall be included when available. Where the substance or mixture has inhibitory effects on the activity of microorganisms, the possible impact on sewage treatment plants shall be mentioned.

Where experimental data are not available, the supplier shall consider whether reliable and relevant information obtained from models can be provided.

For substances subject to registration, summaries of the information derived from the application of Annexes VII to XI of this Regulation shall be included.